RT Journal Article
SR Electronic
T1 Polycythaemia rubra vera and hairy cell leukaemia in the same patient: studies on the spleen
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 1312
OP 1315
DO 10.1136/jcp.35.12.1312
VO 35
IS 12
A1 Mufti, GJ
A1 Hamblin, TJ
A1 Stevenson, FK
A1 Fitchett, M
YR 1982
UL http://jcp.bmj.com/content/35/12/1312.abstract
AB The first association of polycythaemia rubra vera (PRV) and hairy cell leukaemia (HCL) is reported. The secretion by spleen cells in short term culture of IfGλ to the exclusion κ demonstrated that despite aberrant surface marker studies the HCL was a monoclonal tumour of B cells. Chromosomal studies on splenic cells were not able to demonstrate the common clonal origin of the two tumours.