PT  - JOURNAL ARTICLE
AU  - Poulsen, L O
AU  - Johansen, P
AU  - Jensen, M K
AU  - Freund, L
TI  - Differentiation between Bernard-Soulier syndrome and immune thrombocytopenia by immunostaining of peripheral blood.
AID  - 10.1136/jcp.42.12.1296
DP  - 1989 Dec 01
TA  - Journal of Clinical Pathology
PG  - 1296--1297
VI  - 42
IP  - 12
4099  - http://jcp.bmj.com/content/42/12/1296.short
4100  - http://jcp.bmj.com/content/42/12/1296.full
SO  - J Clin Pathol1989 Dec 01; 42
AB  - Peripheral blood smears from seven patients with Bernard-Soulier syndrome were examined by an immunocytochemical staining procedure using a monoclonal antibody specific for platelet glycoprotein Ib. No platelet staining was observed except for very slight staining of the large sized platelets from one of the patients. Application of the assay to blood smears from 12 patients with immune thrombocytopenia showed that their peripheral platelets stained normally, so the assay can be used to differentiate between immune thrombocytopenia and Bernard-Soulier syndrome and to confirm a diagnosis of the syndrome.