PT  - JOURNAL ARTICLE
AU  - Dhundee, J
AU  - Rigby, H S
TI  - Comparison of two preparatory techniques for urine cytology.
AID  - 10.1136/jcp.43.12.1034
DP  - 1990 Dec 01
TA  - Journal of Clinical Pathology
PG  - 1034--1035
VI  - 43
IP  - 12
4099  - http://jcp.bmj.com/content/43/12/1034.short
4100  - http://jcp.bmj.com/content/43/12/1034.full
SO  - J Clin Pathol1990 Dec 01; 43
AB  - Two methods of preparation of urine for cytology were compared retrospectively. In method 1 cells in the urine were fixed after the preparation of the smear; in method 2 the cells were fixed before smear preparation. Urine cytology reports were correlated with subsequent histological analysis. The specificities of urine cytology using both methods were high (99%). The sensitivity using method 1 was 87%; using method 2 it was 65%. This difference was significant. The cell preparation technique therefore significantly changes the sensitivity of urine cytology. Cellular fixation after smear preparation is preferable to smear preparation after fixation.