RT Journal Article
SR Electronic
T1 Comparison of two preparatory techniques for urine cytology.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 1034
OP 1035
DO 10.1136/jcp.43.12.1034
VO 43
IS 12
A1 Dhundee, J
A1 Rigby, H S
YR 1990
UL http://jcp.bmj.com/content/43/12/1034.abstract
AB Two methods of preparation of urine for cytology were compared retrospectively. In method 1 cells in the urine were fixed after the preparation of the smear; in method 2 the cells were fixed before smear preparation. Urine cytology reports were correlated with subsequent histological analysis. The specificities of urine cytology using both methods were high (99%). The sensitivity using method 1 was 87%; using method 2 it was 65%. This difference was significant. The cell preparation technique therefore significantly changes the sensitivity of urine cytology. Cellular fixation after smear preparation is preferable to smear preparation after fixation.