PT - JOURNAL ARTICLE AU - Schofield, K P AU - Evans, D I TI - Diamond-Blackfan syndrome and neutropenia. AID - 10.1136/jcp.44.9.742 DP - 1991 Sep 01 TA - Journal of Clinical Pathology PG - 742--744 VI - 44 IP - 9 4099 - http://jcp.bmj.com/content/44/9/742.short 4100 - http://jcp.bmj.com/content/44/9/742.full SO - J Clin Pathol1991 Sep 01; 44 AB - Neutropenia is a rare complication of Diamond-Blackfan syndrome (congenital hypoplastic anaemia). Three patients are reported: all had neutropenia as well as anaemia, and to investigate the cause of the neutropenia culture of bone marrow for granulocyte-macrophage colony forming cells (GMCFCs) was performed. Two cases had a low incidence of GMCFCs, but the third case had a high incidence. These findings suggest that myeloid precursors can be abnormal in Diamond-Blackfan syndrome and that the mechanism of neutropenia may, like that of anaemia, vary from patient to patient.