PT  - JOURNAL ARTICLE
AU  - Takanami, I
AU  - Imamura, T
AU  - Hashizume, T
AU  - Kikuchi, K
AU  - Yamamoto, Y
AU  - Kodaira, S
TI  - Transforming growth factor beta 1 as a prognostic factor in pulmonary adenocarcinoma.
AID  - 10.1136/jcp.47.12.1098
DP  - 1994 Dec 01
TA  - Journal of Clinical Pathology
PG  - 1098--1100
VI  - 47
IP  - 12
4099  - http://jcp.bmj.com/content/47/12/1098.short
4100  - http://jcp.bmj.com/content/47/12/1098.full
SO  - J Clin Pathol1994 Dec 01; 47
AB  - AIMS--To evaluate the efficacy of transforming growth factor beta (TGF-beta) for the prognosis of pulmonary adenocarcinoma. METHODS--TGF-beta was detected immunohistochemically using the avidin-biotin-peroxidase complex technique in resected pulmonary adenocarcinomas from 88 patients. RESULTS--Of the 88 patients, 39 were TGF-beta negative and 45 TGF-beta positive. The five year survival rate was 56% for the TGF-beta negative and 16% for the TGF-beta positive group. CONCLUSIONS--TGF-beta can be used as a prognostic factor in pulmonary adenocarcinoma.