RT Journal Article
SR Electronic
T1 Clear cell carcinoma of the ovary arising in a mucinous cystadenoma
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 938
OP 939
DO 10.1136/jcp.53.12.938
VO 53
IS 12
A1 Dutt, N
A1 Berney, D M
YR 2000
UL http://jcp.bmj.com/content/53/12/938.abstract
AB A 57 year old woman presented complaining of increasing abdominal swelling of six months duration. A mixed solid cystic left ovarian tumour measuring 24 cm in diameter was excised. Histology showed numerous cysts lined by benign mucinous epithelium blending imperceptibly into borderline clear cell and mucinous areas that in turn merged with an invasive clear cell carcinoma. To the best of our knowledge, this is the first reported case of clear cell carcinoma arising in a mucinous cystadenoma. The implications for the previously postulated pathogenesis of these tumours are discussed.