PT - JOURNAL ARTICLE AU - Soilleux, E J AU - Coleman, N TI - Expression of DC-SIGN in human foreskin may facilitate sexual transmission of HIV AID - 10.1136/jcp.57.1.77 DP - 2004 Jan 01 TA - Journal of Clinical Pathology PG - 77--78 VI - 57 IP - 1 4099 - http://jcp.bmj.com/content/57/1/77.short 4100 - http://jcp.bmj.com/content/57/1/77.full SO - J Clin Pathol2004 Jan 01; 57 AB - This study demonstrates that the human immunodeficiency virus (HIV) binding C-type lectin DC-SIGN is coexpressed with CD4 and CCR5 on dendritic cells/macrophages in human foreskin. It is hypothesised that DC-SIGN may contribute to the sexual transmission of HIV in the foreskin, by enabling infection of permissive cells in cis and/or in trans.