RT Journal Article
SR Electronic
T1 Postmortem diagnosis of chronic granulomatous disease: how worthwhile is it?
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 1339
OP 1341
DO 10.1136/jcp.2004.025098
VO 58
IS 12
A1 Lakshman, R
A1 Bruce, S
A1 Spencer, D A
A1 Crawford, D
A1 Galloway, A
A1 Cooper, P N
A1 Barge, D
A1 Roos, D
A1 Flood, T J
A1 Abinun, M
YR 2005
UL http://jcp.bmj.com/content/58/12/1339.abstract
AB A previously healthy 11 year old boy died unexpectedly after a rapid course of progressive pneumonia. Postmortem microbiology and histopathology suggested an underlying diagnosis of chronic granulomatous disease. This was confirmed by neutrophil oxidative burst and gene mutation analysis of other family members, one of whom benefited from early bone marrow transplantation.