PT - JOURNAL ARTICLE AU - Nakayama, H AU - Enzan, H AU - Yamamoto, M AU - Miyazaki, E AU - Yasui, W TI - High molecular weight caldesmon positive stromal cells in the capsule of hepatocellular carcinomas AID - 10.1136/jcp.2004.016279 DP - 2004 Jul 01 TA - Journal of Clinical Pathology PG - 776--777 VI - 57 IP - 7 4099 - http://jcp.bmj.com/content/57/7/776.short 4100 - http://jcp.bmj.com/content/57/7/776.full SO - J Clin Pathol2004 Jul 01; 57 AB - Aims: To investigate the smooth muscle nature of the stromal cells in the capsule of hepatocellular carcinomas. Methods: Immunohistochemical analysis using monoclonal antibody to high molecular weight caldesmon (HCD), a highly specific marker for smooth muscle cells, was performed in 33 encapsulated hepatocellular carcinomas and adjacent hepatic tissues. Results: HCD positive stromal cells were detected in the capsule of 21 of the 33 hepatocellular carcinomas examined. Conclusions: The capsule of hepatocellular carcinomas contains smooth muscle cells.