RT Journal Article
SR Electronic
T1 High molecular weight caldesmon positive stromal cells in the capsule of hepatocellular carcinomas
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 776
OP 777
DO 10.1136/jcp.2004.016279
VO 57
IS 7
A1 Nakayama, H
A1 Enzan, H
A1 Yamamoto, M
A1 Miyazaki, E
A1 Yasui, W
YR 2004
UL http://jcp.bmj.com/content/57/7/776.abstract
AB Aims: To investigate the smooth muscle nature of the stromal cells in the capsule of hepatocellular carcinomas. Methods: Immunohistochemical analysis using monoclonal antibody to high molecular weight caldesmon (HCD), a highly specific marker for smooth muscle cells, was performed in 33 encapsulated hepatocellular carcinomas and adjacent hepatic tissues. Results: HCD positive stromal cells were detected in the capsule of 21 of the 33 hepatocellular carcinomas examined. Conclusions: The capsule of hepatocellular carcinomas contains smooth muscle cells.