PT - JOURNAL ARTICLE AU - Al-Daraji, W I AU - Abdellaoui, A AU - Salman, W D TI - Osseous metaplasia in a tubular adenoma of the colon AID - 10.1136/jcp.2004.020685 DP - 2005 Feb 01 TA - Journal of Clinical Pathology PG - 220--221 VI - 58 IP - 2 4099 - http://jcp.bmj.com/content/58/2/220.short 4100 - http://jcp.bmj.com/content/58/2/220.full SO - J Clin Pathol2005 Feb 01; 58 AB - An 85 year old woman presented with a one month history of change in her bowel habits in the form of alternating diarrhoea and constipation. She also noted some rectal bleeding. Flexible sigmoidoscopy revealed a 1.5 cm polyp 30 cm from the anus. The polyp was removed during the sigmoidoscopy by electrocautery and sent for histological examination. The polyp was a tubular adenoma with mild dysplasia. The adenoma contained numerous foci of metaplastic bone. These consisted of irregular islands of mineralised osteoid bone rimmed by a layer of scattered osteoblasts. This is the first case of osseous metaplasia in a tubular adenoma of the colon to be reported.