RT Journal Article
SR Electronic
T1 A patient with a VEGF and endostatin producing gastrointestinal autonomic nerve tumour
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 536
OP 538
DO 10.1136/jcp.2003.012393
VO 57
IS 5
A1 Hansma, A H G
A1 van Hensbergen, Y
A1 Kuenen, B C
A1 van Diest, P J
A1 Hanemaaijer, R
A1 Meijer, S
A1 Pinedo, H M
A1 Hoekman, K
YR 2004
UL http://jcp.bmj.com/content/57/5/536.abstract
AB Tumour associated neovascularisation has been characterised as chaotic and insufficient. This report details the results of the analysis of angiogenic factors in tumour cyst fluid, pleural fluid, and blood from a patient with a gastrointestinal autonomic nerve tumour. The tumour produced vascular endothelial growth factor and endostatin in large quantities, which may explain the dysfunctional angiogenesis and tendency to bleeding seen in this tumour type.