RT Journal Article SR Electronic T1 Pancreatic polypeptide cell hyperplasia of the pancreas JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 1087 OP 1090 DO 10.1136/jcp.2005.030478 VO 59 IS 10 A1 Albazaz, R A1 Da Costa, P E A1 Verbeke, C S YR 2006 UL http://jcp.bmj.com/content/59/10/1087.abstract AB A case of pancreatic polypeptide cell hyperplasia in a 76-year-old man who presented with subacute bowel pseudo-obstruction is reported. A computed tomography scan incidentally showed a pancreatic head lesion that was resected by pancreaticoduodenectomy. Histological examination showed expansion of the endocrine pancreas with increased numbers of pancreatic polypeptide cells in irregularly enlarged islets, ragged endocrine cell clusters, ductulo-insular complexes and microadenomas. The clinicopathological features of this rare and poorly understood condition are discussed.