PT - JOURNAL ARTICLE AU - Alwaheeb, S AU - Rambaldini, G AU - Boerner, S AU - Coiré, C AU - Fiser, J AU - Asa, S L TI - Worrisome histologic alterations following fine-needle aspiration of the parathyroid AID - 10.1136/jcp.2005.029017 DP - 2006 Oct 01 TA - Journal of Clinical Pathology PG - 1094--1096 VI - 59 IP - 10 4099 - http://jcp.bmj.com/content/59/10/1094.short 4100 - http://jcp.bmj.com/content/59/10/1094.full SO - J Clin Pathol2006 Oct 01; 59 AB - Fine-needle aspiration (FNA) is a procedure that is increasingly being performed. Artefacts occurring after FNA are reported to complicate the histological analysis of the tissue, mainly in the thyroid; WHAFFT (worrisome histologic alterations following FNA of thyroid) is well documented in the literature. The case of a male patient with hypercalcaemia who was subsequently found to have a nodule in the thyroid gland is reported here. He underwent FNA, followed by a total thyroidectomy and parathyroidectomy. The abnormality in the parathyroid gland showed worrisome histological changes that were suspicious of a malignant lesion, resembling the changes seen in the thyroid gland after FNA. Parathyroid cells were identified by a review of the previous FNA. The concept of WHAFFT, which can mimic the features of malignancy in the parathyroid gland, is therefore introduced.