PT - JOURNAL ARTICLE AU - Serra, S AU - Jani, P A TI - An approach to duodenal biopsies AID - 10.1136/jcp.2005.031260 DP - 2006 Nov 01 TA - Journal of Clinical Pathology PG - 1133--1150 VI - 59 IP - 11 4099 - http://jcp.bmj.com/content/59/11/1133.short 4100 - http://jcp.bmj.com/content/59/11/1133.full SO - J Clin Pathol2006 Nov 01; 59 AB - The introduction of endoscopy of the upper digestive tract as a routine diagnostic procedure has increased the number of duodenal biopsy specimens. Consequently, the pathologist is often asked to evaluate them. In this review, a practical approach to the evaluation of a duodenal biopsy specimen is discussed. An overview of the handling of specimens is given and the normal histology and commonly encountered diseases are discussed. Finally, a description of commonly seen infections is provided, together with an algorithmic approach for diagnosis.