PT - JOURNAL ARTICLE AU - Carter, Vaughan TI - My approach to cardiothoracic transplantation and the role of the histocompatibility and immunogenetics laboratory in a rapidly developing field AID - 10.1136/jcp.2009.068478 DP - 2010 Mar 01 TA - Journal of Clinical Pathology PG - 189--193 VI - 63 IP - 3 4099 - http://jcp.bmj.com/content/63/3/189.short 4100 - http://jcp.bmj.com/content/63/3/189.full SO - J Clin Pathol2010 Mar 01; 63 AB - Cardiothoracic transplantation presents specific challenges. The lack of long-term replacement therapy (such as dialysis for kidney patients) creates a more urgent situation than for other forms of transplantation, necessitating a different approach. This review looks at ways in which the challenges are being met and the integral role of the histocompatibility and immunogenetics laboratory.