RT Journal Article
SR Electronic
T1 Getting controls under control: the time is now for immunohistochemistry
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 879
OP 882
DO 10.1136/jclinpath-2014-202705
VO 68
IS 11
A1 Torlakovic, Emina Emilia
A1 Nielsen, Søren
A1 Vyberg, Mogens
A1 Taylor, Clive R
YR 2015
UL http://jcp.bmj.com/content/68/11/879.abstract
AB For several decades, immunohistochemistry (IHC), more specifically diagnostic IHC (dIHC), has been considered an art rather than a laboratory test. There was no clarity about what test performance characteristics are relevant to dIHC, test performance characteristics were not fully defined for dIHC and partly as a consequence of that, there were no standardised controls or reference standards. Herein, we discuss the role of standardisation of external controls for test performance characteristics and the role of standardised controls and reference standards for overall standardisation of IHC.