Table 1

Patient and tumour characteristics and results of molecular and immunohistochemical analyses

Variable	Categorisation	n analysable*	Per cent
Total (n=174)*
Clinicopathological data
Age at diagnosis (median, range)		69.5 years (32–92)
	<70 years	87	50.0
	≥70 years	87	50.0
Sex
	Female	43	24.7
	Male	131	75.3
Tumour stage48†
	pTa	90	51.7
	pT1	68	39.1
	pT2	13	7.5
	pT3	2	1.1
	pT4	1	0.6
Histological grade48†
	G1	44	25.3
	G2	87	50.0
	G3	43	24.7
Histological grade49‡
	Low grade	101	58.0
	High grade	73	42.0
Adjacent carcinoma in situ
	No	158	90.8
	Yes	16	9.2
Multiplicity
	Solitary	124	71.3
	Multifocal	50	28.7
Growth pattern
	Papillary	159	91.4
	Solid	15	8.6
Immunohistochemistry (IHC)
Cx43
	Score 0	56	32.2
	Score 1+	87	50.0
	Score 2+	31	17.8
Ki67 labelling index
	≤10%	108	62.1
	>10%	66	37.9