Univariate analysis of clinicopathological parameters with disease-free survival
| Factor | Number of events | HR (95% CI) | p Value |
|---|---|---|---|
| Age | |||
| <Mean age | 5/43 | Reference | |
| ≥Mean age | 5/54 | 3.92 (0.50 to 30.7) | 0.193 |
| Size | |||
| <Mean size | 3/57 | Reference | |
| ≥Mean size | 7/37 | 0.736 (0.09 to 6.07) | 0.776 |
| Ethnicity | |||
| Chinese | 4/66 | Reference | |
| Malay | 1/8 | 0.12 (0.01 to 1.32) | 0.083 |
| Indian | 0/3 | 0.85 (0.02 to 31.03) | 0.928 |
| Others | 5/20 | 0.01 (0.01 to 2.49) | 0.513 |
| Grade | |||
| Benign | 3/57 | Reference | |
| Borderline | 5/29 | 0.84 (0.01 to 63.89) | 0.935 |
| Malignant | 2/11 | 0.46 (0.02 to 11.77) | 0.639 |
| Stromal hypercellularity | |||
| Mild | 1/37 | Reference | |
| Moderate | 8/51 | 0.37 (0.01 to 245.55) | 0.762 |
| Marked | 1/9 | 3.64 (0.02 to 589.29) | 0.619 |
| Stromal atypia | |||
| Mild | 6/68 | Reference | |
| Moderate | 3/22 | 1.66 (0.004 to 749.20) | 0.871 |
| Marked | 1/7 | 1.18 (0.01 to 210.94) | 0.951 |
| Mitotic activity (per 10 HPFs) | |||
| 0–3 | 3/57 | Reference | |
| 4–9 | 4/23 | 0.34 (0.03 to 4.36) | 0.405 |
| ≥10 | 3/17 | 1.07 (0.112 to 10.16) | 0.954 |
| Stromal overgrowth | |||
| Absent | 7/83 | Reference | |
| Present | 3/14 | 8.19 (0.00 to 7.22) | 0.953 |
| Microscopic borders | |||
| Circumscribed | Reference | ||
| Permeative | 1.45 (0.13 to 15.92) | 0.759 | |
| MED12 mutations | |||
| Present | 3/60 | Reference | |
| Absent | 7/37 | 24.76 (2.45 to 247.7) | 0.006 |