Multivariable Cox proportional hazards regression model for survival
| Parameter | Variable | HR | 95% CI | p Value |
|---|---|---|---|---|
| Tumour stage | pT3/4 vs 1/2 | 2.2 | 1.62 to 3.05 | <0.0001 |
| Grade | G3/4 vs 1/2 | 1.26 | 0.90 to 1.72 | 0.1807 |
| Nodal status | N1/2 vs N0 | 2.72 | 2.24 to 3.32 | <0.0001 |
| Tumour localisation | left hemicolon vs right hemicolon | 0.94 | 0.77 to 1.14 | 0.5267 |
| Ki67 IHC | Low/intermediate vs high | 1.41 | 1.08 to 1.90 | 0.0121 |
| p53 IHC | Positive vs negative | 0.89 | 0.74 to 1.07 | 0.2201 |
| β-Catenin IHC | Weak/strong vs negative | 1.11 | 0.85 to 1.46 | 0.4677 |