Clinical, radiological and pathological features of non-cystic neutrophilic granulomatous mastitis/granulomatous mastitis (non-CNGM) cohort with positive microbiological studies
Case | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Clinical features | ||||||||
Age (years) | 25–29 | 30–34 | 40–44 | 30–34 | 45–49 | 30–34 | 30–34 | 40–44 |
Gravida | G0P0 | G2P2 | G2P1 | G2P2 | G3P2 | G3P2A1 | G1P1 | N/A |
Breast feeding | N | Y | N/A | Y | Y | Y | Y | N/A |
Mass | Y (unifocal) | Y (multifocal) | Y (multifocal) | Y (multifocal) | Y (unifocal) | Y (unifocal) | N | N/A |
Size (cm) | 2.0 | 6.4 | 3.8 | 1.5 | 1.2 | 0.8 | N/A | N/A |
Pain | Y | Y | Y | Y | N | Y | N | N/A |
Spontaneous drainage | Y | Y | Y | N | N | N | N | N/A |
Skin irritation | Y | Y | Y | N | N | Y | N | N/A |
Microbiology | ||||||||
Gram stain | Not done | – | – | – | – | – | Not done | – |
Culture | + (non-Corynebacterial organisms) | + (Corynebacterium spp) | + (Corynebacterium spp) | + (non-Corynebacterial organisms) | Not done | Not done | Not done | Not done |
16S rRNA | + | + | + | + | + | + | + | + |
SS | + (Uncultured bacterium) | – | + (Uncultured bacterium) | + (non-Corynebacterial organisms) | + (non-Corynebacterial organisms) | + (non-Corynebacterial organisms) | + (non-Corynebacterial organisms) | + (non-Corynebacterial organisms) |
Treatment | ||||||||
Antibiotics | Cefalexin, trimethoprim/ sulfamethoxazole | Clindamycin, cefalexin, ceftriaxone | Clavulin, doxycycline | Clavulin | N | Y | N | N/A |
Steroids | N | N | N | N | N | N | N | N/A |
Drainage | Y | Y | Y | N | N | N | N | N/A |
Excision | N | N | N | N | N | N | N | N/A |
Outcomes | ||||||||
Resolution | Y | Y | N | Y | Y | Y | N/A | N/A |
Recurrence | N | N | N | N | N | N | N/A | N/A |
–, negative; +, positive; N, no; N/A, not available; 16S rRNA, 16S ribosomal RNA; SS, Sanger sequencing; Y, yes.