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Increasing recognition of haemoglobin Le Lamentin
  1. K Wiener1,
  2. X McFarlane2,
  3. B N Green3
  1. 1Department of Clinical Biochemistry, North Manchester General Hospital, Manchester, M8 5RB, UK
  2. 2Department of Gastroenterology, North Manchester General Hospital
  3. 3Micromass UK Ltd, 3 Tudor Road, Altrincham, Cheshire WA14 5RZ, UK

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      The haemoglobin variant Le Lamentin (α20 His → Gln) was first described in 1982 in a negro family in the French West Indies.1 Subsequently, it has been reported in a Japanese family2 and in a Spanish family,3 and recently it was found in a British white man whose haemoglobin displayed an unusual peak when his blood was being assayed for glycated haemoglobin (haemoglobin A1c) by high performance liquid chromatography (HPLC).4 …

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