Accuracy and stability of saliva as a sample for reverse transcription PCR detection of SARS-CoV-2

Yoshifumi Uwamino; Mika Nagata; Wataru Aoki; Yuta Fujimori; Terumichi Nakagawa; Hiromitsu Yokota; Yuko Sakai-Tagawa; Kiyoko Iwatsuki-Horimoto; Toshiki Shiraki; Sho Uchida; Shunsuke Uno; Hiroki Kabata; Shinnosuke Ikemura; Hirofumi Kamata; Makoto Ishii; Koichi Fukunaga; Yoshihiro Kawaoka; Naoki Hasegawa; Mitsuru Murata

doi:10.1136/jclinpath-2020-206972

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Accuracy and stability of saliva as a sample for reverse transcription PCR detection of SARS-CoV-2

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Yoshifumi Uwamino Department of Laboratory Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan Department of Infectious Diseases, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Mika Nagata Clinical Laboratory, Keio University Hospital, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Wataru Aoki Clinical Laboratory, Keio University Hospital, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Yuta Fujimori Clinical Laboratory, Keio University Hospital, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Terumichi Nakagawa Clinical Laboratory, Keio University Hospital, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Hiromitsu Yokota Clinical Laboratory, Keio University Hospital, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Yuko Sakai-Tagawa Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan PubMed articles Google scholar articles
Kiyoko Iwatsuki-Horimoto Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan PubMed articles Google scholar articles
Toshiki Shiraki Department of Laboratory Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Sho Uchida Department of Infectious Diseases, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Shunsuke Uno Department of Infectious Diseases, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Hiroki Kabata Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Shinnosuke Ikemura Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Hirofumi Kamata Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Makoto Ishii Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Koichi Fukunaga Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Yoshihiro Kawaoka Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA PubMed articles Google scholar articles
Naoki Hasegawa Department of Infectious Diseases, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles
Mitsuru Murata Department of Laboratory Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan PubMed articles Google scholar articles

Correspondence to Dr Yoshifumi Uwamino, Department of Laboratory Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan; uwamino{at}keio.jp

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Uwamino Y, Nagata M, Aoki W, et al

Accuracy and stability of saliva as a sample for reverse transcription PCR detection of SARS-CoV-2

Journal of Clinical Pathology 2021;74:67-68.

Publication history

Received July 22, 2020
Accepted September 1, 2020
First published September 14, 2020.

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December 11, 2020

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© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ. This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.https://bmj.com/coronavirus/usage

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